LEISHMANIA AMAZONENSIS RESISTANCE IN MURINE MACROPHAGES: ANALYSIS OF POSSIBLE MECHANISMS.


The Great Wall of Jimbour: Heritage and the Cultural Landscape

On the Darling Downs in Queensland stands one of the most majestic and charming homestead residences from the nineteenth century called Jimbour House.Best known for its homestead complex, Rests comprising heritage listed buildings and ancillary structures, the property at Jimbour has a lesser known but equally significant relic: an expansive dry-st

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Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

Abstract The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections.Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses, with concomitant reduction in viral load.In a previous report, we showed that

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Integrated PacBio SMRT and Illumina sequencing uncovers transcriptional and physiological responses to drought stress in whole-plant Nitraria tangutorum

IntroductionNitraria tangutorum Bobr., a prominent xerophytic shrub, exhibits remarkable adaptability to harsh environment and plays a significant part in preventing desertification in northwest China owing to its exceptional drought and salinity tolerance.MethodsTo investigate the drought-resistant mechanism underlying N.tangutorum, we treated 8-w

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Sensitivity of Standardized Precipitation and Evapotranspiration Index (SPEI) to the choice of SPEI probability distribution and evapotranspiration method

Study region: The state of Oklahoma located in the Southern Plains region of the United States.Study focus: The standardized precipitation evapotranspiration index (SPEI) is a widely used meteorological drought index that incorporates potential evapotranspiration (PET) into a precipitation-based index.However, the understanding of the appropriate P

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